About Summit:

Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational

bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).

• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.

Overview of Role:

Reporting to the Senior Accounting Manager, the Senior Accountant will be an integral member of the Accounting team. This role will be focused on the preparation of monthly journal entries and ensuring completeness and accuracy of the Company’s expenses.

Role and Responsibilities:

• Review contracts for new POs to ensure proper accounting for expenses, prepaids, and accruals

• Assist in closing cash, prepaid, and accruals, including preparing journal entries and performing account reconciliation

• Prepare and run consolidation on a monthly basis

• Analyze intercompany transactions, specifically support the calculation of intercompany cross charges

• Prepare monthly and quarterly fluctuation analyses of income statement and balance sheet

• Assist in preparing statutory financials for foreign entities

• Assist with internal and external auditor requests

• Participate in process improvements, financial system implementations and/or enhancements

• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Minimum bachelor's degree in accounting/finance

• Minimum 4+ years of experience in accounting

• Strong understanding of GAAP, internal controls, SOX controls and month-end close procedures required

• Results-oriented, strong organizational skills, and time management skills with ability to multi-task

• A team player willing to step in and help with other areas of accounting

• Excellent analytical, interpersonal, verbal, and written communication skills

• Superb analytical, strategic, and critical thinking skills, with impeccable attention to detail, and strong prioritization and problem-solving skills

• Demonstrated ability to operate in a fast-paced environment

• Attention to detail, accuracy and confidentiality

• Excellent organizational, management, analytical & decision-making skills

• An ability to work well cross functionally and across geographies

• Impeccable integrity and a strong work ethic

The pay range for this role is $134,500-$158,000 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.