About Summit:

Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).

• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.

Overview:

As a key member of the Market Access leadership team, the Executive Director, US Payer & Account Management will help lead the preparation, development, and execution of market access account strategies for a new oncology investigational asset, ivonescimab. This is a critical customer facing role to helping to ensure broad access, reimbursement, and patient affordability. The individual will be responsible for building and maintaining relationships with key stakeholders, including PBMs, GPOs, Government Channel customers (e.g., Medicaid, VA/DoD), and Integrated Delivery Networks (IDNs). Additionally, the Executive Director, US Payer & Account Management will lead the field account team and collaborate closely with internal teams to integrate customer and market insights into pricing, contracting, and market access strategies and plans.

Roles and Responsibilities:

• Team Leadership: Build, train, and lead the account management field team (Payer, GPO, and other Access Stakeholders) to develop and execute strategic business plans that align with overall objectives, maximize product access, and ensure reimbursement.
• Stakeholder Engagement: Establish and maintain relationships with key decision-makers, including Formulary, P&T, and Pathway leaders, Medical & Pharmacy Directors, Oncology GPOs, and other population-based stakeholders to secure appropriate access and optimal product positioning.
• Leadership and Influence: Demonstrate leadership among various customer groups and Access stakeholders, including Payers, MACs, Oncology GPOs, Academic Institutions and IDNs, Oncology Alliances and Supergroups, Pathway Committee members, and others (State Societies, COA, NCODA, etc.).
• Cross-functional Collaboration: Partner with internal teams (Market Access, Medical Affairs, HEOR, Regulatory, Legal, Finance, Marketing, Sales, etc.) to address reimbursement challenges and develop coordinated solutions that are compliant and effective.
• Strategy Development: Co-create strategies, tools, and tactics for the field team to communicate the product value proposition effectively. Collaborate on pricing and contracting strategies, HEOR evidence generation plans, patient support programs, payer marketing initiatives, and account management approaches.
• Alignment and Negotiation: Lead discussions with internal and external partners to ensure alignment on access, coverage, and reimbursement strategies.
• Culture and Performance: Foster a high-performance culture within the field team by promoting accountability, urgency, ethical behavior, and professional development.
• Industry Insight: Stay informed on healthcare industry trends, payer policies, reimbursement processes, and competitive activity. Provide strategic insights to inform decision-making, access strategies, and product launches.
• Compliance: Ensure all Market Access initiatives are developed and executed in compliance with legal, regulatory, and ethical standards.
• Adaptability: Ability to work effectively in a fast-paced and dynamic environment, balancing multiple priorities and meeting deadlines.
• All other duties as assigned

Experience, Education, and Specialized Knowledge and Skills:

• Bachelor’s degree in business, healthcare, or a related field; advanced degree preferred.
• Minimum of 15+ years of experience in payer and/or GPO strategy, pricing, and reimbursement within the pharmaceutical industry.
• Minimum of 7+ years of focused account management experience in the oncology access marketplace.
• Demonstrated success in engaging with US payers, MACs, GPOs, PBMs, and IDNs.
• Strong understanding of the US healthcare payer/access landscape and regulatory environment.
• Excellent strategic thinking, leadership, negotiation, and relationship management skills.
• Ability to lead cross-functional teams and drive complex projects to completion.
• Exceptional communication and presentation skills.
• Successful record of achieving and maintaining compliance with all applicable regulatory, legal, and operational rules.
• Travel: Ability to travel to support business priorities as needed.

The pay range for this role is $260,000-$280,000 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.