About Summit:

Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).

• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.

Overview of Role:

The Senior Director, US Patient Engagement will play a pivotal role in shaping and executing patient engagement strategies for Ivonescimab. This leadership position requires a deep understanding of the oncology landscape, patient needs, and the ability to collaborate across functions to drive patient-centric initiatives. This role will report into the Head of US Commercial.

Role and Responsibilities:

• Develop and implement comprehensive patient engagement strategies that align with the company's oncology marketing goals and objectives:
• Integrate patient insights into commercial marketing strategies to enhance product positioning, messaging, and outreach efforts.
• Develop patient marketing strategies and promotional content, including educational content and campaigns
• Create programs and materials to aid in initiation, adherence, and retention.
• Coordinate with patient support programs, including educational resources, patient assistance programs, and community outreach initiatives.
• Work closely with clinical, regulatory, marketing, medical, patient advocacy access and sales teams to ensure patient engagement efforts are integrated across all stages of product development and commercialization.
• Collaborate with Patient Advocacy and Access teams on patient-facing work.
• Manage patient marketing agencies and vendors.
• Utilize patient feedback and data analytics to continuously improve patient engagement strategies and measure the impact of marketing initiatives.
• Track trends to enhance the patient engagement strategy
• Ensure compliance with regulatory requirements and ethical standards across all patient engagement activities.
• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelors degree required; advanced degree in a relevant field (e.g., public health, healthcare administration, business administration, marketing, etc.) strongly preferred

• Minimum of 12+ years of experience in patient engagement, commercial marketing, or related roles within the pharmaceutical industry

• Prior experience supporting patient engagement strategy and initiatives of oncology product launches

• Proven track record of developing and executing successful patient engagement strategies from a marketing perspective

• Strong understanding of the oncology landscape and patient needs

• Excellent communication, leadership, and interpersonal skills

• Ability to work collaboratively across functions and with external partners

• Experience with data analytics and patient feedback mechanisms

• Knowledge of regulatory requirements and ethical standards in patient engagement

The pay range for this role is $221,000 to $277,000 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.