Location: Princeton, NJ ONSITE

*Relocation support will be considered for this role

About Summit:

Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

• HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).

• HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.

• HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.

Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.

Overview of Role:

The Executive Director of US Marketing - NSCLC will lead the development and execution of comprehensive marketing strategies to drive the growth and success of our oncology portfolio, with a specific focus on Non-Small Cell Lung Cancer (NSCLC). This role requires a strategic leader with deep expertise in oncology marketing, strong cross-functional collaboration skills, and a proven ability to optimize resource allocation for maximum ROI. This role will report into the Head of US Commercial.

Role and Responsibilities:

• Develop and implement overall marketing strategies for the NSCLC portfolio to achieve business objectives and drive market growth

• Lead teams in the development of the future vision of the brand, including future indications

• Lead the development and execution of marketing initiatives targeting healthcare professionals (HCPs), patients, and digital platforms, ensuring cohesive and impactful campaigns

• Manage and mentor a high-performing marketing team, fostering a collaborative and innovative environment to achieve strategic goals

• Serve as the primary point of contact for cross-functional teams, ensuring alignment and seamless execution of marketing strategies across scientific, clinical, and commercial functions

• Drive consistent marketing vision across all channels including sales, digital, patient, and access

• Integrate commercial strategies with scientific and clinical insights, as well as market dynamics, to ensure relevance and effectiveness in the oncology landscape

• Drive regional and key customer strategy and engagement

• Oversee the marketing budget and resource allocation, optimizing investments to maximize return on investment (ROI) and drive business growth

• Develop strategic partnerships with key stakeholders and external partners to enhance market presence and drive brand growth

• Monitor competitive landscape and industry trends to inform strategic planning and maintain a competitive edge

• Ensure compliance with regulatory and legal requirements in all marketing activities

• All other duties as assigned

Experience, Education and Specialized Knowledge and Skills:

• Bachelor's degree in Marketing, Business, Life Sciences, or related field; advanced degree preferred

• Minimum of 15+ years of experience in pharmaceutical marketing with a focus in oncology

• Experience with blockbuster drug commercial launches in NSCLC/NDCLC and/or solid tumors within the past 5 years

• Proven track record of developing and executing successful marketing strategies in the oncology space that drive growth

• Strong leadership and business acumen

• Excellent cross-functional collaboration and communication skills

• Ability to analyze market data and derive actionable insights to drive strategy

• Exceptional budget management and resource allocation skills

The pay range for this role is $221,500 - $277,500 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.

Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at recruiting@smmttx.com to obtain prior written authorization before referring any candidates to Summit.